Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.64 |
| ▸ | F10 | P00742 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7403758 | 0.86 | F2 (0.61) | F2 | |
| Hydrochloric Acid SCHEMBL7369618 | 0.83 | F2 (0.78) | F2PRSS1 | |
| Hydrochloric Acid SCHEMBL7371422 | 0.81 | F2 (0.79) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7367776 | 0.79 | F2 (0.86) | F2 | |
| SCHEMBL7715240 | 0.78 | F2 (1.00) | F2 | |
| Trifluoroacetic Acid SCHEMBL7364412 | 0.76 | F2 (0.49) | F2PRSS1 | |
| SCHEMBL7371121 | 0.73 | F2 (1.00) | F2PRSS1 | |
| SCHEMBL7403262 | 0.73 | F2 (0.63) | F2 | |
| SCHEMBL5856303 | 0.73 | F2 (0.79) | F2 | |
| SCHEMBL7371718 | 0.73 | F2 (1.00) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387911-B1 | Pyrazinone thrombin inhibitors | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |