Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.50 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.50 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP2 | O95551 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720493 | 0.81 | S100A4 (0.57) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721587 | 0.81 | S100A4 (0.50) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL27714060 | 0.79 | BACE1 (0.66) | S100A4MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7716521 | 0.78 | MEN1 (0.40) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7721606 | 0.77 | S100A4 (0.47) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7719640 | 0.72 | S100A4 (0.50) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL7720787 | 0.72 | S100A4 (0.44) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL21469198 | 0.71 | S100A4 (0.64) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL27781074 | 0.71 | S100A4 (0.64) | S100A4MEN1KMT2ATDP1GUCY1B2 | |
| SCHEMBL22270544 | 0.70 | DPP4 (0.44) | S100A4MEN1KMT2ATDP1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391064-B1 | DYEING HAIR WITH AMINE QUINOLONE DERIVATIVES | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | claimed |
| EP-0984010-B1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | OREAL (FR) | 2001-06-20 | — | — | EP | claimed |
| EP-0984010-A1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | L'OREAL (FR) | 2000-03-08 | — | — | EP | claimed |
| US-6391064-B1 | DYEING HAIR WITH AMINE QUINOLONE DERIVATIVES | L'OREAL S.A. (FR) | 2002-05-21 | — | — | US | disclosed |
| EP-0984010-B1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | OREAL (FR) | 2001-06-20 | — | — | EP | disclosed |
| EP-0984010-A1 | Use in hair dyes of quinolin-5,8-diones or quinoxalin-5,8-diones condensed with substituted pyrroles, anilines or indoles | L'OREAL (FR) | 2000-03-08 | — | — | EP | disclosed |