Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76907 | 0.92 | ALDH1A1 (0.45) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL1720541 | 0.84 | ALDH1A1 (0.39) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL7969217 | 0.84 | ALDH1A1 (0.39) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL1278439 | 0.81 | ALDH1A1 (0.43) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL1871824 | 0.80 | ATM (0.41) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL2400361 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL8053231 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| Hydrochloric Acid SCHEMBL1874071 | 0.80 | ALDH1A1 (0.42) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL501542 | 0.77 | HSP90AA1 (0.43) | ALDH1A1NR1I2LMNACYP2C9MIF | |
| SCHEMBL5365402 | 0.77 | MEN1 (0.41) | ALDH1A1NR1I2LMNACYP2C9MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387992-B1 | HEAT, OXIDATION AND LIGHT RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-14 | — | — | US | disclosed |