Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL732167 | 0.82 | CYP3A4 (0.47) | ALDH1A1TDP1L3MBTL1HTR2CHTR2B | |
| SCHEMBL29765571 | 0.82 | CYP3A4 (0.47) | ALDH1A1TDP1L3MBTL1HTR2CHTR2B | |
| SCHEMBL13904847 | 0.78 | ACP3 (0.42) | P2RX7ACP3IDO1TDO2ALDH1A1 | |
| SCHEMBL28092744 | 0.78 | ACP3 (0.39) | P2RX7ACP3MPOIDO1TDO2 | |
| SCHEMBL686397 | 0.77 | ACP3 (0.53) | P2RX7HSD11B1ACP3IDO1TDO2 | |
| SCHEMBL334979 | 0.76 | P2RX7 (0.47) | P2RX7HSD11B1ACP3MPOIDO1 | |
| SCHEMBL1727762 | 0.76 | P2RX7 (0.47) | P2RX7HSD11B1ACP3MPOIDO1 | |
| SCHEMBL29808963 | 0.76 | P2RX7 (0.47) | P2RX7HSD11B1ACP3MPOIDO1 | |
| SCHEMBL1258401 | 0.76 | P2RX7 (0.47) | P2RX7HSD11B1ACP3MPOIDO1 | |
| SCHEMBL30303206 | 0.76 | P2RX7 (0.47) | P2RX7HSD11B1ACP3MPOIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380243-B1 | INCLUDING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, VARICELLA-ZOSTER VIRUS, HUMAN HERPESVIRUSES- 6 AND -7, AND KAPOSI HERPESVIRUS. | AMERICAN HOME PRODUCTS CORPORATION | 2002-04-30 | — | — | US | disclosed |