Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CCR2 | P41597 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7719878 | 1.00 | EPHX1 (0.51) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL7719843 | 1.00 | EPHX1 (0.51) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL5144107 | 0.90 | EPHX1 (0.61) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL4003535 | 0.80 | EPHX1 (0.40) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL28826584 | 0.80 | EPHX1 (0.67) | EPHX1EPHX2CCR2GAAKMT2A | |
| Hydrochloric Acid SCHEMBL4152526 | 0.79 | EPHX1 (0.40) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL4153131 | 0.78 | EPHX1 (0.41) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL19173472 | 0.77 | LMNA (0.53) | GAAKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL16064910 | 0.77 | EPHX1 (0.63) | EPHX1EPHX2CCR2GAAKMT2A | |
| SCHEMBL16064908 | 0.77 | GAA (0.66) | EPHX1EPHX2CCR2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-1125922-A1 | PYRROLIDINE COMPOUNDS AND MEDICINAL UTILIZATION THEREOF | Welfide Corporation (JP) | 2001-08-22 | — | — | EP | disclosed |