Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461846 | 0.85 | TSHR (0.56) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| Formaldehyde SCHEMBL8658362 | 0.85 | TSHR (0.56) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL231282 | 0.84 | TSHR (0.61) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL476827 | 0.84 | TSHR (0.61) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL4226282 | 0.83 | TSHR (0.58) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7053203 | 0.83 | TSHR (0.58) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL4588282 | 0.82 | TSHR (0.52) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL981848 | 0.82 | GRM5 (0.54) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL6702666 | 0.81 | TSHR (0.56) | TSHRGRM5ALDH1A1NPC1RAB9A | |
| SCHEMBL203767 | 0.81 | TSHR (0.56) | TSHRGRM5ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | claimed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | claimed |
| US-6391916-B1 | ANTITUMOR AGENTS | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2002-05-21 | — | — | US | disclosed |
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| US-5512209-A | IMPROVED RESPONSE CHARACTERISTICS AND HIGH CONTRAST; DISPOSING COMPOSITION BETWEEN ELECTRODE PLATES | CANON KABUSHIKI KAISHA (JP) | 1996-04-30 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |
| EP-0374095-A2 | Piperidine derivatives | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| US-4101676-A | Diphenylpropylamines to treat depression | BEECHAM GROUP LIMITED (GB) | 1978-07-18 | — | — | US | disclosed |