Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476827 | 0.96 | TSHR (0.61) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL6702666 | 0.88 | TSHR (0.56) | TSHRNPC1GRM5ALDH1A1RAB9A | |
| SCHEMBL7147100 | 0.86 | NPC1 (0.57) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL23258691 | 0.86 | ALDH1A1 (0.55) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL21962241 | 0.86 | TSHR (0.54) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL9956104 | 0.86 | TSHR (0.54) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL7720076 | 0.85 | TSHR (0.58) | TSHRNPC1GRM5ALDH1A1RAB9A | |
| SCHEMBL6905812 | 0.84 | TSHR (0.52) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL30984454 | 0.84 | TSHR (0.52) | TSHRNPC1GRM5PLA2G4BALDH1A1 | |
| SCHEMBL24737439 | 0.84 | TSHR (0.52) | TSHRNPC1GRM5PLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767140-A | USEFUL FOR TREATING AIDS | SOUTHERN RESEARCH INSTITUTE (US) | 1998-06-16 | — | — | US | disclosed |