SCHEMBL7720121

SCHEMBL7720121

CC(=O)Nc1cccc2cc(S(=O)(=O)O)cc(O)c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 2/20 0.67
APEX1 P27695 1/20 0.55
TSHR P16473 1/20 0.47
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
PRMT1 Q99873 1/20 0.45
NT5E P21589 2/20 0.44
DUSP5 Q16690 1/20 0.43
KLK7 P49862 1/20 0.43
CA1 P00915 4/20 0.40
CA2 P00918 4/20 0.40
CA9 Q16790 4/20 0.40
CASR P41180 1/20 0.40
CYP2C9 P11712 2/20 0.40
CYP1A2 P05177 1/20 0.40
MAPK1 P28482 1/20 0.40
DNASE1L3 Q13609 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11773973 0.89 CASP6 (0.59) CASP6APEX1TSHRALDH1A1MAPT
SCHEMBL10789555 0.86 CASP6 (0.57) CASP6APEX1TSHRALDH1A1MAPT
SCHEMBL29516436 0.85 APEX1 (0.64) CASP6APEX1ALDH1A1MAPTPRMT1
SCHEMBL29575995 0.85 APEX1 (0.64) CASP6APEX1ALDH1A1MAPTPRMT1
SCHEMBL1413179 0.85 APEX1 (0.64) CASP6APEX1ALDH1A1MAPTPRMT1
SCHEMBL26885744 0.85 APEX1 (0.52) CASP6APEX1TSHRPRMT1NT5E
SCHEMBL8010537 0.84 APEX1 (0.63) CASP6APEX1ALDH1A1MAPTPRMT1
SCHEMBL5147103 0.84 APEX1 (0.63) CASP6APEX1ALDH1A1MAPTPRMT1
Phenol SCHEMBL11600632 0.83 APEX1 (0.69) CASP6APEX1ALDH1A1KDM4EPRMT1
SCHEMBL13619183 0.83 APEX1 (0.81) CASP6APEX1ALDH1A1CYP2C9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6376656-B1 DISAZO DYES, TRIAZINE DYES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2002-04-23 US disclosed
CN-1067419-C Reactive dyestuffs their preparation and their use BAYER AG (DE) 2001-06-20 CN disclosed
EP-0774493-B1 Fiber-reactive azo dyestuffs, process for their preparation and use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2001-04-04 EP disclosed
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 US disclosed
EP-0627471-B1 Reactive dyes BAYER AG (DE) 2000-08-23 EP disclosed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-6046311-A Water-soluble fiber-reactive dyes, preparation thereof and use thereof DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2000-04-04 US disclosed
US-6025478-A HIGH REACTIVITY AND FIXING CAPACITY, GOOD LOW TEMPERATURE DYEING, GOOD COLOR INTENSITY, LIGHTFASTNESS, WASHFASTNESS BAYER AG (DE) 2000-02-15 US disclosed
EP-0122881-A1 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1984-10-24 EP disclosed
EP-0112797-A1 Process for dyeing or printing cellulose-containing fibrous material with reactive dyes CIBA-GEIGY AG (CH) 1984-07-04 EP disclosed
EP-0089923-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-09-28 EP disclosed
EP-0085654-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-08-10 EP disclosed
EP-0085025-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1983-08-03 EP disclosed
EP-0076782-A2 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1983-04-13 EP disclosed
EP-0074928-A2 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
EP-0059355-A2 Use of reactive dyestuffs in dyeing and printing of hydroxylgroups containing fibrous materials BAYER AG (DE) 1982-09-08 EP disclosed
US-4325869-A CONTAINING A PYRIMIDINE RING AND ONE OR MORE AZO GROUPS CIBA-GEIGY CORPORATION (US) 1982-04-20 US disclosed
US-4261889-A TRIAZINE DYES FOR COTTON CIBA-GEIGY CORP. (US) 1981-04-14 US disclosed