Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 5/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15154600 | 0.86 | MEN1 (0.62) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7573812 | 0.84 | EGFR (0.53) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10674197 | 0.83 | EGFR (0.62) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25823030 | 0.82 | EGFR (0.51) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15154474 | 0.81 | SRC (0.60) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7723300 | 0.81 | EGFR (0.56) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7723296 | 0.80 | EGFR (0.48) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5165239 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1SRCALDH1A1 | |
| SCHEMBL46596 | 0.77 | EGFR (0.69) | EGFRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL15154546 | 0.76 | NPC1 (0.53) | EGFRMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395750-B1 | Includes laquinimod, N-ethyl-N-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxo-quinoline-3-carboxamide and its salts; breat or prostate cancer | ACTIVE BIOTECH AB (SE) | 2002-05-28 | — | — | US | claimed |