Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10232756 | 0.78 | KMT2A (0.53) | LMNAHTTKMT2APIK3CDKDM4E | |
| SCHEMBL654972 | 0.78 | PIK3CD (0.45) | PIK3CDALDH1A1SLC2A1 | |
| SCHEMBL5072 | 0.76 | — | — | |
| SCHEMBL13850080 | 0.75 | KMT2A (0.46) | LMNAHTTKMT2APIK3CDKDM4E | |
| SCHEMBL436938 | 0.74 | ALDH1A1 (0.46) | LMNAHTTKMT2AKDM4EALDH1A1 | |
| SCHEMBL22996251 | 0.73 | KMT2A (0.48) | LMNAHTTKMT2APIK3CDKDM4E | |
| SCHEMBL13907142 | 0.73 | KMT2A (0.48) | LMNAHTTKMT2APIK3CDKDM4E | |
| SCHEMBL4658 | 0.72 | — | — | |
| SCHEMBL3550224 | 0.71 | PIK3CD (0.39) | KMT2APIK3CDALDH1A1 | |
| SCHEMBL6124873 | 0.70 | PIK3CD (0.50) | KMT2APIK3CDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0598061-B1 | NOVEL 4-OXOCYCLIC UREAS USEFUL AS ANTIARRHYTHMIC AND ANTIFIBRILLATORY AGENTS | PROCTER & GAMBLE PHARMA (US) | 2002-07-17 | — | — | EP | disclosed |