Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | TGM1 | P22735 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7729539 | 0.92 | NR1H2 (0.38) | NR1H2TGM2CYP1A2POLBCYP3A4 | |
| SCHEMBL7722084 | 0.88 | NR1H2 (0.39) | NR1H2TGM2CYP1A2POLBCYP3A4 | |
| SCHEMBL7721995 | 0.88 | NR1H2 (0.39) | NR1H2TGM2CYP1A2POLBCYP3A4 | |
| SCHEMBL7729001 | 0.81 | NR1H2 (0.44) | NR1H2 | |
| SCHEMBL31000687 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3PTPN1MMP2ANPEP | |
| SCHEMBL9601879 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3PTPN1MMP2ANPEP | |
| SCHEMBL29851070 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3PTPN1MMP2ANPEP | |
| SCHEMBL17317642 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3PTPN1MMP2ANPEP | |
| SCHEMBL6185885 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3PTPN1MMP2ANPEP | |
| SCHEMBL6184330 | 0.79 | NR1H2 (0.40) | NR1H2NR1H3PTPN1MMP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399629-B1 | PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY | MICROCIDE PHARMACEUTICALS, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |