SCHEMBL7722281

SCHEMBL7722281

CC(C)[C@H](N)C(=O)OC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
KIF11 P52732 8/20 0.42
SLC15A1 P46059 1/20 0.40
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
KCNN4 O15554 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
SLC7A5 Q01650 1/20 0.38
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30534307 1.00 CYP1A2 (0.47) CYP1A2CYP2D6KIF11SLC15A1MAPT
SCHEMBL6746230 0.88 CYP1A2 (0.46) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL2771121 0.87 CYP1A2 (0.45) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL29697636 0.86 CYP1A2 (0.50) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL27707192 0.82 CYP2D6 (0.50) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL10464550 0.82 CYP1A2 (0.48) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL30800300 0.80 CYP1A2 (0.47) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL27587690 0.79 CYP1A2 (0.42) CYP1A2CYP2D6KIF11MAPTKMT2A
SCHEMBL7359300 0.79 CYP1A2 (0.46) CYP1A2CYP2D6KIF11MAPTKMT2A
Methoxytriphenylmethane SCHEMBL11619895 0.78 SLC7A5 (0.50) CYP1A2CYP2D6KIF11SLC15A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279655-A Pharmaceutical use of cyclic peptide compounds 中外制药株式会社 2023-12-22 CN disclosed
CN-116615411-A Process for producing peptide compound containing N-substituted amino acid residue 中外制药株式会社 2023-08-18 CN disclosed
WO-2002083606-A1 A LINKER SYSTEM FOR THE SYNTHESIS AND SCREENING OF COMBINATORIAL LIBRARIES OF POLYAMINE DERIVATIVES ON WATER COMPATIBLE SUPPORTS UNIVERSITY OF ALBERTA (CA) 2002-10-24 WO disclosed