Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 14/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722281 | 0.87 | CYP1A2 (0.47) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL30534307 | 0.87 | CYP1A2 (0.47) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL6746230 | 0.85 | CYP1A2 (0.46) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL7359300 | 0.83 | CYP1A2 (0.46) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL29697636 | 0.83 | CYP1A2 (0.50) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL27707192 | 0.80 | CYP2D6 (0.50) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL10464550 | 0.79 | CYP1A2 (0.48) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL30800300 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL27587690 | 0.76 | CYP1A2 (0.42) | CYP1A2CYP2D6KIF11MAPTKMT2A | |
| SCHEMBL232514 | 0.75 | KIF11 (0.42) | CYP1A2CYP2D6KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197895-A2 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009032181-A2 | METHODS AND INTERMEDIATES FOR CHEMICAL SYNTHESIS OF POLYPEPTIDES AND PROTEINS | IPSEN PHARMA S.A.S. (FR) | 2009-03-12 | — | — | WO | disclosed |