Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.47 |
| ▸ | PPARA | Q07869 | 19/20 | 0.47 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722485 | 0.94 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL7727703 | 0.89 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL8876911 | 0.86 | PPARG (0.40) | PPARGPPARAPPARD | |
| SCHEMBL7722509 | 0.86 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL7722506 | 0.86 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL5974090 | 0.86 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL7724111 | 0.86 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL7538422 | 0.85 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL7722481 | 0.85 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL5623121 | 0.85 | PPARG (0.64) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700397-B1 | NEW THIAZOLIDINDIONES AND DRUGS CONTAINING THEM | ROCHE DIAGNOSTICS GMBH (DE) | 2002-09-04 | — | — | EP | claimed |
| US-5599826-A | ANTIDIABETIC AGENT | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-04 | — | — | US | claimed |
| US-5599826-A | ANTIDIABETIC AGENT | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-04 | — | — | US | disclosed |