Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.62 |
| ▸ | PPARA | Q07869 | 20/20 | 0.62 |
| ▸ | PPARD | Q03181 | 5/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974090 | 0.99 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5743073 | 0.94 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL5623121 | 0.94 | PPARG (0.64) | PPARGPPARAPPARD | |
| SCHEMBL7727703 | 0.89 | PPARG (0.59) | PPARGPPARAPPARD | |
| SCHEMBL7533421 | 0.86 | PPARG (0.62) | PPARGPPARAPPARD | |
| SCHEMBL7722506 | 0.85 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL7722509 | 0.85 | PPARG (0.49) | PPARGPPARAPPARD | |
| SCHEMBL7722490 | 0.85 | PPARG (0.47) | PPARGPPARAPPARD | |
| SCHEMBL7724111 | 0.85 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL7621884 | 0.84 | PPARG (0.52) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020010345-A1 | Methods for the preparation of 4-hydroxy benzothiophene | JUNGHANS BERND (DE) | 2002-01-24 | — | — | US | disclosed |
| US-6291685-B1 | REACTING 1-(2-THIENYL)ALLYL DERIVATIVE IN SOLVENT MEDIUM CONTAINING BASE AND CARBOXYLIC ACID ANHYDRIDE WITH CARBON MONOXIDE IN PRESENCE OF CARBONYLATION CATALYST TO FORM ESTER COMPOUND; SAPONIFICATION TO FORM 4-HYDROXYBENZOTHIOPHENE | HOFFMANN-LA ROCHE INC. | 2001-09-18 | — | — | US | disclosed |
| EP-1078923-A2 | Process for the preparation of benzothiophene derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020010345-A1 | Methods for the preparation of 4-hydroxy benzothiophene | SLC5A2, TST, SLC5A1 | PPARG 677/4885PPARA 1335/4885PPARD 1114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.