SCHEMBL7722729

SCHEMBL7722729

CCCCCC1CCC(c2cc(F)c(C(F)(F)Oc3cc(F)c(OC(F)(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722727 1.00 MEN1 (0.30) MEN1KMT2A
SCHEMBL7731558 0.97
SCHEMBL7731562 0.97
SCHEMBL7729732 0.92 CYP2C9 (0.34) MEN1KMT2A
SCHEMBL7729727 0.92 CYP2C9 (0.34) MEN1KMT2A
SCHEMBL15744820 0.90 MEN1 (0.31) MEN1KMT2A
SCHEMBL7722879 0.90 MEN1 (0.32) MEN1KMT2A
SCHEMBL7722877 0.90 MEN1 (0.32) MEN1KMT2A
SCHEMBL7732606 0.90 MEN1 (0.32) MEN1KMT2A
SCHEMBL7732605 0.90 MEN1 (0.32) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed