SCHEMBL7722732

SCHEMBL7722732

CCCCc1ccc(C(F)(F)Oc2ccc(CCc3cc(F)c(OC(F)(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
PPARG P37231 2/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 2/20 0.34
ALOX5 P09917 1/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7732528 0.96 HTR2A (0.36) DAOHDAC3HDAC1HDAC2GPR84
SCHEMBL7735461 0.94 HDAC3 (0.36) DAOHDAC3HDAC1HDAC2GPR84
SCHEMBL7733390 0.93 DAO (0.37) DAOGPR84TUBB4ATUBBTUBA3C
SCHEMBL7731930 0.91 S1PR1 (0.34) HDAC3HDAC1HDAC2S1PR1S1PR3
SCHEMBL7731928 0.91 RARB (0.39) HDAC3HDAC1HDAC2PPARGS1PR1
SCHEMBL7734772 0.90 HTR2A (0.37) HDAC3HDAC1HDAC2PPARGALOX5
SCHEMBL7722843 0.90 DAO (0.36) DAOHDAC3HDAC1HDAC2GPR84
SCHEMBL7734959 0.90 DAO (0.40) DAOGPR84TUBB4ATUBBTUBA3C
SCHEMBL7732500 0.90 HDAC3 (0.33) HDAC3HDAC1HDAC2FFAR4PCSK9
SCHEMBL7722674 0.89 S1PR1 (0.36) DAOPPARGS1PR1S1PR3ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed