Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.39 |
| ▸ | RARA | P10276 | 2/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733508 | 0.97 | RARB (0.44) | RARBRARARARGPPARGPPARA | |
| SCHEMBL7730636 | 0.93 | MAOB (0.35) | RARBRARARARGMAOBPPARG | |
| SCHEMBL7735461 | 0.92 | HDAC3 (0.36) | HDAC3HDAC1HDAC2PPARGPPARA | |
| SCHEMBL12624839 | 0.91 | RARB (0.44) | RARBRARARARGPPARGPPARA | |
| SCHEMBL7722732 | 0.91 | DAO (0.36) | HDAC3HDAC1HDAC2PPARGPPARA | |
| SCHEMBL7731930 | 0.89 | S1PR1 (0.34) | RARBRARARARGHDAC3HDAC1 | |
| SCHEMBL12623053 | 0.88 | RARB (0.42) | RARBRARARARGS1PR1SERPINE1 | |
| SCHEMBL7734772 | 0.88 | HTR2A (0.37) | RARBRARARARGHDAC3HDAC1 | |
| SCHEMBL7730677 | 0.88 | RARB (0.41) | RARBRARARARGMAOBPPARG | |
| SCHEMBL7722612 | 0.88 | PRMT6 (0.38) | PPARGPPARAPRMT6SERPINE1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |