Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722692 | 0.96 | SKP2 (0.35) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL15317519 | 0.95 | S1PR1 (0.34) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL7730380 | 0.93 | S1PR1 (0.35) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL7729099 | 0.91 | HTR2A (0.37) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL14226747 | 0.91 | S1PR1 (0.34) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL12625471 | 0.91 | RARB (0.42) | S1PR1PPARGPPARAFAAHRARB | |
| SCHEMBL7731510 | 0.91 | DAO (0.34) | — | |
| SCHEMBL7730606 | 0.90 | S1PR1 (0.35) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL7733175 | 0.89 | RARB (0.42) | S1PR1PPARGPPARARARBRARA | |
| SCHEMBL7731530 | 0.89 | S1PR1 (0.33) | S1PR1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |