Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 3/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722735 | 0.95 | S1PR1 (0.36) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL14226611 | 0.93 | S1PR1 (0.34) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL14226769 | 0.93 | S1PR1 (0.39) | S1PR1PPARGPPARATHRB | |
| SCHEMBL7722692 | 0.91 | SKP2 (0.35) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL7730606 | 0.90 | S1PR1 (0.35) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL15317521 | 0.89 | DAO (0.33) | S1PR1PPARGPPARA | |
| SCHEMBL7734985 | 0.89 | PTGS2 (0.37) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL7730380 | 0.88 | S1PR1 (0.35) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL14226629 | 0.88 | HTR2A (0.34) | S1PR1PPARGPPARAHTR2AFAAH | |
| SCHEMBL14226557 | 0.87 | RARB (0.40) | S1PR1RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133397-B2 | Tricyclic compound having a plurality of CF2O bonding groups, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20130271719-A1 | TRICYCLIC COMPOUND HAVING A PLURALITY OF CF2O BONDING GROUPS, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2013-10-17 | — | — | US | disclosed |