SCHEMBL7722786

SCHEMBL7722786

CCCCCC1CCC(CCc2ccc(C(F)(F)Oc3cc(F)c(OC(F)(F)F)c(F)c3)c(F)c2)CC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
CYP2C8 P10632 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
S1PR3 Q99500 1/20 0.32
MOGAT2 Q3SYC2 1/20 0.32
HCRTR1 O43613 1/20 0.31
HCRTR2 O43614 1/20 0.31
LYPLA1 O75608 1/20 0.30
LYPLA2 O95372 1/20 0.30
ABHD16A O95870 1/20 0.30
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7722783 1.00 CYP3A4 (0.32) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL7729267 0.97 MOGAT2 (0.32) MOGAT2HCRTR1HCRTR2BCHE
SCHEMBL7729273 0.97 MOGAT2 (0.32) MOGAT2HCRTR1HCRTR2BCHE
SCHEMBL7730996 0.93 HCRTR1 (0.32) HCRTR1HCRTR2
SCHEMBL7730995 0.93 HCRTR1 (0.32) HCRTR1HCRTR2
SCHEMBL7734847 0.91 HCRTR1 (0.32) HCRTR1HCRTR2
SCHEMBL7731452 0.91 CYP3A4 (0.33) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL7734843 0.91 HCRTR1 (0.32) HCRTR1HCRTR2
SCHEMBL7731457 0.91 CYP3A4 (0.33) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19
SCHEMBL7730633 0.89 CYP3A4 (0.31) CYP3A4CYP2C8CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0786445-B1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORP (JP) 2002-07-17 EP disclosed
US-5858270-A Difluorooxymethane derivative and liquid crystal composition CHISSO CORPORATION (JP) 1999-01-12 US disclosed
EP-0786445-A1 DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CHISSO CORPORATION (JP) 1997-07-30 EP disclosed