Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730996 | 1.00 | HCRTR1 (0.32) | HCRTR1HCRTR2GCGRBACE1CTSD | |
| SCHEMBL7729267 | 0.94 | MOGAT2 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL7729273 | 0.94 | MOGAT2 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL7734847 | 0.94 | HCRTR1 (0.32) | HCRTR1HCRTR2BACE1CTSDBACE2 | |
| SCHEMBL7734843 | 0.94 | HCRTR1 (0.32) | HCRTR1HCRTR2BACE1CTSDBACE2 | |
| SCHEMBL7722786 | 0.93 | CYP3A4 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL7722783 | 0.93 | CYP3A4 (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL7733423 | 0.90 | SLC6A2 (0.30) | — | |
| SCHEMBL7733426 | 0.90 | SLC6A2 (0.30) | — | |
| SCHEMBL7730298 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |