Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 9/20 | 0.40 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470777 | 0.97 | TSHR (0.50) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL7735008 | 0.92 | TSHR (0.43) | TSHRHSD17B10CYP19A1MEN1ALDH1A1 | |
| SCHEMBL8472567 | 0.90 | CYP2A6 (0.45) | TSHRHSD17B10HRH3CYP2A6 | |
| SCHEMBL8470570 | 0.89 | TSHR (0.41) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8836848 | 0.88 | TSHR (0.41) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8836568 | 0.86 | RARB (0.43) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8470743 | 0.86 | TSHR (0.37) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8836799 | 0.85 | RARB (0.45) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8836062 | 0.85 | RARB (0.45) | TSHRHSD17B10RARBRARARARG | |
| SCHEMBL8836400 | 0.85 | RARB (0.45) | TSHRHSD17B10RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |