Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470777 | 0.93 | TSHR (0.50) | TSHRHSD17B10KDM1AHRH3CYP2A6 | |
| SCHEMBL8472567 | 0.93 | CYP2A6 (0.45) | TSHRHSD17B10KDM1AHRH3CYP2A6 | |
| SCHEMBL7722802 | 0.92 | TSHR (0.55) | TSHRHSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL8473158 | 0.88 | ALDH1A1 (0.41) | TSHRHSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL8836028 | 0.87 | DAO (0.41) | KDM1AMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8474034 | 0.85 | RARB (0.33) | HSD17B10MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL8836886 | 0.82 | MAOB (0.40) | HRH3DAOFFAR4KIF11 | |
| SCHEMBL8470743 | 0.82 | TSHR (0.37) | TSHRHSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL8470570 | 0.81 | TSHR (0.41) | TSHRHSD17B10MEN1ALDH1A1MAPT | |
| SCHEMBL8836779 | 0.81 | DAO (0.39) | TSHRHSD17B10KDM1AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786445-B1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORP (JP) | 2002-07-17 | — | — | EP | disclosed |
| US-5858270-A | Difluorooxymethane derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0786445-A1 | DIFLUOROXYMETHANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1997-07-30 | — | — | EP | disclosed |