Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.70 |
| ▸ | RXRG | P48443 | 17/20 | 0.70 |
| ▸ | RARG | P13631 | 8/20 | 0.64 |
| ▸ | RARB | P10826 | 7/20 | 0.64 |
| ▸ | RARA | P10276 | 5/20 | 0.64 |
| ▸ | RXRB | P28702 | 13/20 | 0.64 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723187 | 1.00 | RXRA (0.70) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7735393 | 0.89 | RXRA (0.73) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7735391 | 0.89 | RXRA (0.73) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7723119 | 0.82 | RXRA (1.00) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7723117 | 0.82 | RXRA (1.00) | RXRARXRGRARGRARBRARA | |
| SCHEMBL6917140 | 0.82 | RXRA (0.55) | RXRARXRGRARGRARBRARA | |
| SCHEMBL6908851 | 0.81 | RXRA (0.54) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7732977 | 0.81 | RXRA (0.63) | RXRARXRGRARGRARBRARA | |
| SCHEMBL7732981 | 0.81 | RXRA (0.63) | RXRARXRGRARGRARBRARA | |
| SCHEMBL6915803 | 0.80 | RXRA (0.53) | RXRARXRGRARGRARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403638-B1 | COMPOUND FOR USE IN TREATING SKIN DISEASES AND DISORDERS, AND FOR TREATING HYPERVITAMINOSIS A SYNDROME | ALLERGAN SALES, INC. | 2002-06-11 | — | — | US | disclosed |