Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 16/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31483558 | 0.85 | CTSK (0.49) | TDP1CTSK | |
| SCHEMBL12893562 | 0.85 | CTSK (0.63) | CTSK | |
| SCHEMBL3498473 | 0.82 | CTSK (0.60) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL3818710 | 0.82 | CTSK (0.60) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL6339388 | 0.82 | MEN1 (0.62) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL23009079 | 0.81 | CTSK (0.51) | CTSK | |
| SCHEMBL15221109 | 0.81 | CTSK (0.49) | CTSK | |
| SCHEMBL24906968 | 0.81 | MEN1 (0.54) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL6277041 | 0.80 | MEN1 (0.64) | MEN1GAAKMT2ATDP1CTSK | |
| SCHEMBL20738187 | 0.79 | CTSK (0.47) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |