Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 3/20 | 0.41 |
| ▸ | MVD | P53602 | 4/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prop-2-Ynyl Diphosphate SCHEMBL1651692 | 0.96 | BTN3A1 (0.44) | BTN3A1MVDFDPSBLMTDP1 | |
| Prop-2-Ynyl Diphosphate SCHEMBL13738981 | 0.85 | BTN3A1 (0.41) | BTN3A1MVDFNTAPGGT1BFNTB | |
| SCHEMBL28992521 | 0.80 | ACHE (0.35) | BTN3A1ACHE | |
| Hydrochloric Acid SCHEMBL11243597 | 0.80 | ACHE (0.38) | ACHE | |
| SCHEMBL11952601 | 0.79 | ACHE (0.41) | BTN3A1ACHE | |
| SCHEMBL3262560 | 0.77 | — | — | |
| SCHEMBL29174378 | 0.75 | BTN3A1 (0.57) | BTN3A1MVDFDPSBLMTDP1 | |
| SCHEMBL28278159 | 0.75 | BTN3A1 (0.48) | BTN3A1MVDFDPSBLMTDP1 | |
| Hydrochloric Acid SCHEMBL11244451 | 0.75 | ACHE (0.38) | FDPSBLMTDP1ACHE | |
| Hydrochloric Acid SCHEMBL11244454 | 0.75 | ACHE (0.38) | FDPSBLMTDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399335-B1 | MIXING POLYMERASE AND NUCLEOSIDE TRIPHOSPHATE HAVING A GAMMA PHOSPHATE PHOSPHOESTER-LINKED FUNCTIONAL GROUP, INCUBATING SO THAT POLYMERASE CATALYZES CLEAVAGE BETWEEN ALPHA AND BETA PHOSPHATES AND LIBERATES PYROPHOSPHATE WITH FUNCTIONAL GROUP | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. | 2002-06-04 | — | — | US | disclosed |
| WO-2001048235-A2 | GAMMA-PHOSPHOESTER NUCLEOSIDE TRIPHOSPHATES | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) | 2001-07-05 | — | — | WO | disclosed |