SCHEMBL7723295

SCHEMBL7723295

CO[Si](OC)(OC)c1cccc(C(F)(F)F)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.44
TSHR P16473 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MAPT P10636 2/20 0.43
LMNA P02545 1/20 0.43
IDO1 P14902 2/20 0.41
IDH2 P48735 1/20 0.40
CES2 O00748 1/20 0.40
MGLL Q99685 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
HTR2A P28223 1/20 0.40
HTR2C P28335 1/20 0.40
HTR2B P41595 1/20 0.40
NPSR1 Q6W5P4 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15750812 0.87 L3MBTL1 (0.42) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL15737040 0.87 HTR2A (0.41) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL15736292 0.87 HTR2A (0.41) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL15733442 0.87 L3MBTL1 (0.40) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL15736663 0.87 L3MBTL1 (0.40) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL15736195 0.83 L3MBTL1 (0.42) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL23040277 0.82 NR1H3 (0.47) MAPK1TSHRHSD17B10
SCHEMBL15737457 0.82 MAOB (0.49) IDO1SMN1; SMN2KDM4EALDH1A1GAA
SCHEMBL15736648 0.81 L3MBTL1 (0.45) MAPK1TSHRL3MBTL1MAPTLMNA
SCHEMBL15738538 0.81 L3MBTL1 (0.45) MAPK1TSHRL3MBTL1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117138836-A Oxide/iodine composite particles and dispersion of oxide/iodine composite particles 中国石油化工股份有限公司 2023-12-01 CN claimed
CN-116120601-A Preparation method and application of in-situ fluorine functionalized crosslinked hydroxyl-terminated polydimethylsiloxane membrane 常州大学 2023-05-16 CN claimed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN claimed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN claimed
CN-117138836-A Oxide/iodine composite particles and dispersion of oxide/iodine composite particles 中国石油化工股份有限公司 2023-12-01 CN disclosed
CN-116120601-A Preparation method and application of in-situ fluorine functionalized crosslinked hydroxyl-terminated polydimethylsiloxane membrane 常州大学 2023-05-16 CN disclosed
CN-112142660-B Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2021-11-23 CN disclosed
WO-2021122431-A1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-06-24 WO disclosed
EP-3838964-A1 POLYURETHANE FOAMS BASED ON POLYETHER CARBONATE POLYOLS Covestro Deutschland AG (DE) 2021-06-23 EP disclosed
US-20210122928-A1 CHARGE-TRANSPORTING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2021-04-29 US disclosed
CN-112142660-A Method for simply, conveniently and efficiently synthesizing 4-aryl butyric acid derivative 淮阴师范学院 2020-12-29 CN disclosed
US-10727410-B2 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-07-28 US disclosed
US-20170218128-A1 Curable Silicone Resin Composition, Cured Object Obtained Therefrom, and Optical Semiconductor Device Formed Using Same CENTRAL GLASS COMPANY, LIMITED (JP) 2017-08-03 US disclosed
CN-106574118-A Curable silicone resin composition, cured product thereof, and optical semiconductor device using same 中央硝子株式会社 2017-04-19 CN disclosed
EP-2738230-A1 Surface modifier for transparent oxide electrode, surface-modified transparent oxide electrode, and method for producing surface-modified transparent oxide electrode Shin-Etsu Chemical Co., Ltd. (JP) 2014-06-04 EP disclosed
US-20140147628-A1 Surface Modifier For Transparent Oxide Electrode, Surface-Modified Transparent Oxide Electrode, And Method For Producing Surface-Modified Transparent Oxide Electrode SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-05-29 US disclosed
US-6399733-B1 SILICONES MITSUBISHI DENKI KABUSHIKI KAISHA (JP) 2002-06-04 US disclosed