SCHEMBL7723346

SCHEMBL7723346

CCCCC[C@H]1CC[C@H](c2ccc(I)c(OC)c2)CC1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 5/20 0.39
PDE4B Q07343 3/20 0.39
PDE4C Q08493 3/20 0.39
PDE4D Q08499 3/20 0.39
QDPR P09417 2/20 0.37
CYP2C9 P11712 1/20 0.37
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.36
ACHE P22303 1/20 0.35
HTR4 Q13639 1/20 0.35
SPHK1 Q9NYA1 2/20 0.35
TRPV1 Q8NER1 1/20 0.34
S1PR1 P21453 1/20 0.34
SGPL1 O95470 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25426622 0.83 QDPR (0.49) PDE4APDE4BPDE4CPDE4DQDPR
SCHEMBL24426577 0.83 PDE4A (0.39) PDE4APDE4BPDE4CPDE4DQDPR
SCHEMBL10979654 0.82 KDM1A (0.46) PDE4APDE4BPDE4CPDE4DCYP2C9
SCHEMBL10979652 0.82 KDM1A (0.46) PDE4APDE4BPDE4CPDE4DCYP2C9
SCHEMBL872280 0.81 CYP2C9 (0.39) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL872279 0.81 CYP2C9 (0.39) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL11066880 0.81 KDM1A (0.45) PDE4APDE4BPDE4CPDE4DCYP2C9
SCHEMBL11066887 0.81 KDM1A (0.45) PDE4APDE4BPDE4CPDE4DCYP2C9
SCHEMBL2868886 0.80 SPHK1 (0.39) CYP2C9MAPTMEN1KMT2AALDH1A1
SCHEMBL21321635 0.79 KDM1A (0.43) PDE4APDE4BPDE4CPDE4DCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372153-B1 HIGHER DIELECTRIC ANISOTROPY, EXCELLENT IN MISCIBILITY WITH OTHER LIQUID CRYSTALLINE COMPOUNDS, LOW VISCOSITY, STABLE CHEMICALLY AND PHYSICALLY CHISSO CORPORATION (JP) 2002-04-16 US disclosed
EP-1020423-A1 FLUOROALKOXYBENZENE DERIVATIVES HAVING ETHER BOND, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORPORATION (JP) 2000-07-19 EP disclosed