Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493900 | 0.85 | KMT2A (0.53) | GPR119FAAHKDM4EPKMPDE4A | |
| SCHEMBL7732370 | 0.84 | KDM4E (0.67) | GPR119FAAHKDM4EPKMPDE4A | |
| SCHEMBL20015578 | 0.84 | GPR119 (0.59) | GPR119FAAHKDM4EPKMCETP | |
| SCHEMBL16616925 | 0.84 | GPR119 (0.65) | GPR119KDM4EPKM | |
| SCHEMBL1714269 | 0.83 | GPR119 (0.64) | GPR119 | |
| SCHEMBL3096959 | 0.82 | GPR119 (0.67) | GPR119SIGMAR1 | |
| SCHEMBL3146175 | 0.82 | GPR119 (0.60) | GPR119KDM4EPKM | |
| SCHEMBL17961712 | 0.82 | GPR119 (0.58) | GPR119KDM4EPKM | |
| SCHEMBL1575722 | 0.82 | GPR119 (0.57) | GPR119FAAHKDM4EPKM | |
| SCHEMBL2340177 | 0.82 | GPR119 (0.71) | GPR119FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399619-B1 | PREVENTION AND TREATMENT OF AIDS AND VIRAL INFECTION BY HIV | MERCK & CO., INC. | 2002-06-04 | — | — | US | disclosed |