Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19301334 | 0.80 | FOLH1 (0.50) | LAP3FOLH1RNPEPSLC7A5CACNA2D1 | |
| SCHEMBL4063502 | 0.78 | LAP3 (0.34) | LAP3FOLH1RNPEPSLC7A5CACNA2D1 | |
| SCHEMBL30741400 | 0.73 | FFAR3 (0.36) | ALDH1A1FFAR3MMP1MMP2MMP3 | |
| SCHEMBL609300 | 0.72 | RNPEP (0.44) | LAP3RNPEPSLC7A5CACNA2D1CACNB3 | |
| SCHEMBL28022769 | 0.71 | FOLH1 (0.46) | LAP3FOLH1RNPEPSLC7A5CACNA2D1 | |
| SCHEMBL606964 | 0.70 | RNPEP (0.43) | RNPEPSLC7A5CACNA2D1CACNB3CACNA1C | |
| SCHEMBL12570564 | 0.67 | RNPEP (0.39) | RNPEPSLC7A5CACNA2D1CACNB3CACNA1C | |
| SCHEMBL7806306 | 0.67 | SLC7A5 (0.44) | FOLH1RNPEPSLC7A5CACNA2D1CACNB3 | |
| SCHEMBL8850372 | 0.67 | RNPEP (0.39) | FOLH1RNPEPSLC7A5CACNA2D1CACNB3 | |
| SCHEMBL1166910 | 0.67 | RNPEP (0.39) | FOLH1RNPEPSLC7A5CACNA2D1CACNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395894-B2 | BACTERICIDES | MERCK & CO., INC. | 2002-05-28 | — | — | US | disclosed |