Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723555 | 0.95 | L3MBTL1 (0.32) | POLBMAPK1L3MBTL1 | |
| SCHEMBL16248496 | 0.79 | POLB (0.39) | POLBMAPK1TSHRGRM2GRM3 | |
| SCHEMBL5519757 | 0.73 | POLB (0.43) | POLBMAPK1TSHRGRM2GRM3 | |
| SCHEMBL5517151 | 0.72 | MAPK1 (0.53) | POLBMAPK1TSHRALDH1A1 | |
| SCHEMBL28553312 | 0.72 | MAPK1 (0.53) | POLBMAPK1TSHRALDH1A1 | |
| SCHEMBL28551224 | 0.72 | POLB (0.47) | POLBMAPK1TSHRTDP1ALDH1A1 | |
| SCHEMBL5523436 | 0.72 | POLB (0.47) | POLBMAPK1TSHRTDP1ALDH1A1 | |
| SCHEMBL28564418 | 0.71 | POLB (0.55) | POLBMAPK1TSHRALDH1A1 | |
| SCHEMBL28560041 | 0.71 | POLB (0.40) | POLBMAPK1TSHRTDP1ALDH1A1 | |
| SCHEMBL5529388 | 0.71 | POLB (0.40) | POLBMAPK1TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1227078-A1 | DICARBOXYLIC DIESTER, PROCESS FOR PRODUCING THE SAME, AND REFRIGERATING MACHINE LUBRICATING OIL COMPRISING THE ESTER | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 2002-07-31 | — | — | EP | disclosed |