Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.95 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.95 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.95 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.95 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.95 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.95 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.95 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.95 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.95 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.95 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.95 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.95 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.95 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.95 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.95 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.80 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylbutanoic Acid SCHEMBL21219015 | 0.98 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL1716 | 0.98 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL1021513 | 0.98 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL29272542 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL31228551 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL2010634 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL29272534 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL726614 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL28684695 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| Phenylbutanoic Acid SCHEMBL27900207 | 0.95 | HDAC1 (0.95) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110062633-A | Tyrosine derivatives and compositions comprising the same | 迪美公司 | 2019-07-26 | — | — | CN | claimed |
| CN-109549918-A | Ophthalmic pharmaceutical composition, ophthalmic medicine box and medical application thereof | 沈阳兴齐眼药股份有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-109553608-A | The purposes of a kind of five yuan of 6-membered heterocyclic compounds and preparation method thereof and treatment tumour | 北京大学 | 2019-04-02 | — | — | CN | claimed |
| CN-109475624-A | The adjusting that the structure that chromosome -1 is expressed maintains | 瓦尔基里治疗有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-109381451-A | Magnesium threonate and combinations thereof for treating tumour | 无锡脑镁素生物医药科技有限公司 | 2019-02-26 | — | — | CN | claimed |
| CN-109311802-A | Chlorambucil formulations | 珠海贝海生物技术有限公司 | 2019-02-05 | — | — | CN | claimed |
| CN-109152774-A | Combination treatment of ocular inflammatory conditions and diseases | 奥尔德拉医疗公司 | 2019-01-04 | — | — | CN | claimed |
| CN-108866185-A | Method for predicting the medicine response in cancer patient | 肿瘤学风险公司 | 2018-11-23 | — | — | CN | claimed |
| CN-108449940-A | Conjugated bridge linkers to cell binding molecules | 苏州美康加生物科技有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-108289964-A | Novel linkers and their use for specific coupling of drugs and biomolecules | 苏州美康加生物科技有限公司 | 2018-07-17 | — | — | CN | claimed |
| CN-106232109-A | Pharmaceutical composition for cancer treatment comprising gossypol and phenformin as active ingredients | 国立癌中心 | 2016-12-14 | — | — | CN | claimed |
| CN-101535003-B | Method of doping surfaces | ENBIO LTD | 2012-11-28 | — | — | CN | claimed |
| CN-101965351-A | Benzofuran pyrimidinones | EXELIXIS INC | 2011-02-02 | — | — | CN | claimed |
| CN-101535003-A | Method of doping surfaces | ENBIO LTD (IE) | 2009-09-16 | — | — | CN | claimed |
| CN-101193644-A | Treatment of hyperproliferative diseases with anthraquinones | NOVACEA INC (US) | 2008-06-04 | — | — | CN | claimed |
| CN-101180061-A | Compounds, and compositions containing the compounds, and method for treatment of metastatic melanoma and other cancers | PROMETIC BIOSCIENCES INC (CA) | 2008-05-14 | — | — | CN | claimed |
| CN-1853642-A | Combined preparations comprising morpholine anthracyclines and anticancer agent | PHARMACIA & UPJOHN SPA (IT) | 2006-11-01 | — | — | CN | claimed |
| CN-1507869-A | Combined preparation containing morpholine anthracyclines and anticancer agent | �������Ŷ���Լ��������˾ | 2004-06-30 | — | — | CN | claimed |
| CN-1349406-A | Combined preparation containing morpholine anthracyclines and anticancer agent | PHARMACIA & UPJOHN SPA (IT) | 2002-05-15 | — | — | CN | claimed |
| CN-1040987-A | Be used for drug release and chromatographic composition and method thereof | AUSTRALIAN COMMERCIAL RESEARCH (AU) | 1990-04-04 | — | — | CN | claimed |