SCHEMBL7723661

SCHEMBL7723661

Oc1c(Cl)cc(Cl)cc1C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
ALDH1A1 P00352 4/20 0.48
CYP3A4 P08684 3/20 0.48
RECQL P46063 2/20 0.48
HSD17B10 Q99714 2/20 0.48
KDM4E B2RXH2 4/20 0.42
MAPT P10636 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
CYP2C9 P11712 2/20 0.41
CYP2D6 P10635 1/20 0.41
PTGDR2 Q9Y5Y4 8/20 0.41
PTGDR Q13258 5/20 0.41
PTGER2 P43116 1/20 0.41
GAA P10253 3/20 0.40
HPGD P15428 2/20 0.39
SLC22A2 O15244 1/20 0.39
SLC22A1 O15245 1/20 0.39
NR1I2 O75469 1/20 0.39
SLC22A3 O75751 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27878148 0.90 ALDH1A1 (0.54) TSHRALDH1A1CYP3A4RECQLHSD17B10
SCHEMBL23699808 0.81 KDM4E (0.47) HSD17B10KDM4EMAPTMEN1KMT2A
SCHEMBL27679384 0.81 KDM4E (0.44) TSHRKDM4EMAPTMEN1KMT2A
SCHEMBL11774790 0.79 PTGDR2 (0.40) TSHRKDM4EMAPTMEN1KMT2A
SCHEMBL9249778 0.79 AKR1C4 (0.53) ALDH1A1CYP3A4HSD17B10KDM4EMAPT
SCHEMBL13784952 0.78 KDM4E (0.38) TSHRHSD17B10KDM4EMAPTMEN1
SCHEMBL2353146 0.78 ERN1 (0.56) ALDH1A1CYP3A4KDM4EMAPTMEN1
SCHEMBL12459032 0.78 PTGDR2 (0.40) ALDH1A1CYP3A4KDM4EMAPTMEN1
SCHEMBL23699810 0.76 GCGR (0.46) ALDH1A1KDM4EMAPTMEN1KMT2A
SCHEMBL23699823 0.75 PTPN5 (0.46) KDM4EMAPTMEN1KMT2APTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605265-B Acanthol and its synthesis process 广州佳途科技股份有限公司 2023-07-14 CN disclosed
CN-114605265-A Demodex and synthetic method thereof 广州佳途科技股份有限公司 2022-06-10 CN disclosed
US-6399653-B1 METABOLISM DIORDERS; CARDIOVASCULAR DISORDERS; NERVOUS SYSTEM DISORDERS HOECHST AKTIENGESELLSCHAFT (DE) 2002-06-04 US disclosed