Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3361402 | 1.00 | DPP4 (0.58) | DPP4PDE10AOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL3364127 | 0.99 | DPP4 (0.59) | DPP4PDE10AOPRM1OPRD1OPRK1 | |
| SCHEMBL3362959 | 0.84 | DPP4 (0.40) | DPP4PDE10AOPRM1OPRD1OPRK1 | |
| SCHEMBL3362127 | 0.82 | DPP4 (0.60) | DPP4 | |
| Hydrochloric Acid SCHEMBL3361829 | 0.81 | DPP4 (0.61) | DPP4 | |
| SCHEMBL3361000 | 0.78 | DPP4 (0.61) | DPP4 | |
| SCHEMBL7723652 | 0.78 | DPP4 (0.73) | DPP4PDE10A | |
| Hydrochloric Acid SCHEMBL3362995 | 0.77 | DPP4 (0.61) | DPP4 | |
| SCHEMBL3363381 | 0.76 | DPP4 (0.55) | DPP4 | |
| Hydrochloric Acid SCHEMBL3369641 | 0.75 | DPP4 (0.56) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| US-7732446-B1 | Dipeptidyl peptidase inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |