Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 1.00 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.79 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.70 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.69 |
| ▸ | HTR2A | P28223 | 2/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | HTR1A | P08908 | 1/20 | 0.69 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.69 |
| ▸ | FPR3 | P25089 | 1/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | HTR1D | P28221 | 1/20 | 0.69 |
| ▸ | HTR1B | P28222 | 1/20 | 0.69 |
| ▸ | HTR2C | P28335 | 1/20 | 0.69 |
| ▸ | GPR183 | P32249 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724542 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL11744855 | 1.00 | ADRB2 (1.00) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| Hydrochloric Acid SCHEMBL11670656 | 0.98 | ADRB2 (0.97) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL13902861 | 0.93 | ADRB2 (0.87) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL14752727 | 0.93 | ADRB2 (0.87) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL2054489 | 0.93 | ADRB2 (0.87) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL13902986 | 0.93 | ADRB2 (0.87) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL2054491 | 0.93 | ADRB2 (0.87) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL28044430 | 0.92 | ADRB2 (0.85) | ADRB2ADRB1ADRB3SLC6A2HTR2A | |
| SCHEMBL13662070 | 0.90 | ADRB2 (0.84) | ADRB2ADRB1ADRB3SLC6A2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362371-B1 | DIAMINES DISUBSTITUED WITH HYDROXYMETHYL HYDROXYETHYLPHENOL GROUPS; RESPIRATORY SYSTEM DISORDERS, NERVOUS SYSTEM INJURIES, AND PREMATURE LABOR | ADVANCED MEDICINE, INC. | 2002-03-26 | — | — | US | disclosed |
| WO-1999064034-A9 | β2-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE INC (US) | 2000-06-29 | — | — | WO | disclosed |