Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26687978 | 0.92 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTNPC1TDP1ALDH1A1 | |
| SCHEMBL7116626 | 0.92 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTTSHRNPC1TDP1 | |
| SCHEMBL21051883 | 0.91 | SMN1; SMN2 (0.62) | SMN1; SMN2MAPTTSHRNPC1TDP1 | |
| SCHEMBL426382 | 0.89 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTTSHRNPC1TDP1 | |
| SCHEMBL550516 | 0.89 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTTSHRNPC1TDP1 | |
| SCHEMBL7733827 | 0.88 | CACNA1F (0.58) | SMN1; SMN2MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL7734024 | 0.88 | CACNA1F (0.58) | SMN1; SMN2MAPTTSHRTDP1ALDH1A1 | |
| SCHEMBL7665374 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTNPC1TDP1ALDH1A1 | |
| SCHEMBL2616927 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTTSHRNPC1TDP1 | |
| SCHEMBL3299225 | 0.88 | CA12 (0.62) | SMN1; SMN2MAPTNPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085299-A | Plasticizing agent diethyl phthalate hapten and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2015-11-25 | — | — | CN | claimed |
| CN-105085667-A | Diethyl phthalate artificial coating antigen as well as preparation and application thereof | UNIV SHANGHAI JIAOTONG | 2015-11-25 | — | — | CN | claimed |
| CN-105085663-A | Diethyl phthalate artificial immunogen, and preparation and application thereof | UNIV SHANGHAI JIAOTONG | 2015-11-25 | — | — | CN | claimed |
| US-10640510-B2 | Metabotrophic glutamate receptor 5 modulators and methods use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2020-05-05 | — | — | US | disclosed |
| US-20200079778-A9 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | SUNOVION PHARMACEUTICALS INC. | 2020-03-12 | — | — | US | disclosed |
| US-20190135815-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | SUNOVION PHARMACEUTICALS INC (US) | 2019-05-09 | — | — | US | disclosed |
| US-10196399-B2 | Metabotrophic glutamate receptor 5 modulators and methods use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20180037585-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | SUNOVION PHARAMCEUTICALS INC. | 2018-02-08 | — | — | US | disclosed |
| US-9708331-B2 | Metabotrophic glutamate receptor 5 modulators and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2017-07-18 | — | — | US | disclosed |
| US-20160251359-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. | 2016-09-01 | — | — | US | disclosed |
| US-9260452-B2 | Metabotrophic glutamate receptor 5 modulators and methods of use thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2016-02-16 | — | — | US | disclosed |
| CN-100432042-C | Preparation technology of purified 4-nitro phthalic acid | LU XIANCHUN (CN) | 2008-11-12 | — | — | CN | disclosed |
| CN-1651399-A | Preparation technology of purified 4-nitro phthalic acid | LU XIANCHUN (CN) | 2005-08-10 | — | — | CN | disclosed |
| US-6399318-B1 | ANTIGEN WHICH IS CONJUGATE OF CARRIER PROTEIN AND PHTHALIC ACID ESTER OF DEFINED STRUCTURE; FOR DETECTION AND MEASUREMENT OF PLASTICIZERS IN ENVIRONMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| US-4960905-A | CURING AGENT FOR EPOXY RESINS | OCCIDENTAL CHEMICAL CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4827000-A | REACTION OF FLUOROPHTHALIC ANHYDRIDE WITH A PHENOL | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0308863-A2 | Process for the preparation of phenoxy phthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0118543-A1 | SUBSTITUTED N-BENZENESULFONYLOXYPHTHALIMIDES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1984-09-19 | — | — | EP | disclosed |
| WO-1984000888-A1 | SUBSTITUTED N-BENZENESULFONYLOXYPHTHALIMIDES | UNIV SOUTHERN CALIFORNIA (US) | 1984-03-15 | — | — | WO | disclosed |
| US-4002664-A | Manufacture of dimethylaminobenzenecarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DT) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10196399-B2 | Metabotrophic glutamate receptor 5 modulators and methods use thereof | GRM5, GRIK5, GRM2 | SMN1; SMN2 3419/4885MAPT 4094/4885TSHR 481/4885 |
| US-20180037585-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | GRM5, GRIK5, GRM2 | SMN1; SMN2 3419/4885MAPT 4094/4885TSHR 481/4885 |
| US-20160251359-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | GRM5, GRIK5, GRM2 | SMN1; SMN2 2960/4885MAPT 4176/4885TSHR 455/4885 |
| US-20190135815-A1 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | GRM5, GRIK5, GRM2 | SMN1; SMN2 3419/4885MAPT 4094/4885TSHR 481/4885 |
| US-20200079778-A9 | METABOTROPHIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS USE THEREOF | GRM5, GRIK5, GRM2 | SMN1; SMN2 3419/4885MAPT 4094/4885TSHR 481/4885 |
| US-10640510-B2 | Metabotrophic glutamate receptor 5 modulators and methods use thereof | GRM5, GRIK5, GRM2 | SMN1; SMN2 3419/4885MAPT 4094/4885TSHR 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.