SCHEMBL7724216

SCHEMBL7724216

Cc1ccc(CON2CC[CH]CC2)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.35
KDM4A O75164 1/20 0.35
KDM5A P29375 1/20 0.35
KDM2B Q8NHM5 1/20 0.35
KDM4C Q9H3R0 1/20 0.35
KDM5B Q9UGL1 1/20 0.35
IDO1 P14902 3/20 0.33
MGLL Q99685 1/20 0.33
DRD4 P21917 2/20 0.33
CACNA1F O60840 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
DRD1 P21728 1/20 0.33
ADRA1D P25100 1/20 0.33
HTR7 P34969 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
OPRM1 P35372 1/20 0.33
DRD3 P35462 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12016053 0.71 IDO1 (0.42) NPSR1KDM4AKDM5AKDM2BKDM4C
SCHEMBL25394603 0.70 IDO1 (0.66) KDM4AKDM5AKDM2BKDM4CKDM5B
SCHEMBL6301740 0.68 KDM4A (0.38) KDM4AKDM5AKDM2BKDM4CKDM5B
SCHEMBL12960527 0.67 IDO1 (0.43) KDM4AKDM5AKDM2BKDM4CKDM5B
SCHEMBL16179106 0.67 IDO1 (0.44) NPSR1IDO1KMT2AMEN1GAA
SCHEMBL18213801 0.67 IDO1 (0.43) KDM4AKDM5AKDM2BKDM4CKDM5B
SCHEMBL13932525 0.66 AMY1A (0.42) NPSR1IDO1KMT2AMEN1LMNA
SCHEMBL2355598 0.66 TAAR1 (0.40) NPSR1IDO1KMT2AMEN1LMNA
SCHEMBL17918743 0.66 KDM4E (0.56) DRD4CACNA1FCHRM2CHRM1DRD2
SCHEMBL17447266 0.66 KDM4E (0.40) NPSR1KDM4AKDM5AKDM2BKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6395745-B1 STABLE, CRYSTAL STRUCTURE; PLANT EXTRACT GLYCODESIGN, INC. (CA) 2002-05-28 US disclosed