Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | FABP7 | O15540 | 4/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735227 | 1.00 | HPGD (0.44) | HPGDNAAACA1CA2ALDH1A1 | |
| SCHEMBL7737008 | 1.00 | HPGD (0.44) | HPGDNAAACA1CA2ALDH1A1 | |
| SCHEMBL7732300 | 0.87 | FABP7 (0.54) | HPGDALDH1A1MAPTMMP1MMP9 | |
| SCHEMBL7724393 | 0.87 | FABP7 (0.54) | HPGDALDH1A1MAPTMMP1MMP9 | |
| SCHEMBL7734247 | 0.87 | FABP7 (0.54) | HPGDALDH1A1MAPTMMP1MMP9 | |
| SCHEMBL7724385 | 0.86 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL7732999 | 0.86 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL7734167 | 0.86 | MMP1 (0.39) | ALDH1A1MMP1MMP2MMP9MMP12 | |
| SCHEMBL7734190 | 0.86 | FABP7 (0.54) | HPGDALDH1A1FABP7FABP5MAPK1 | |
| SCHEMBL7733042 | 0.86 | FABP7 (0.54) | HPGDALDH1A1FABP7FABP5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407284-B1 | CONTACTING WITH ENZYME; HYDROLYSIS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-18 | — | — | US | disclosed |