Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7724428 | 1.00 | SIGMAR1 (0.50) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7729813 | 0.91 | HTR2A (0.44) | SIGMAR1DRD4HTR2ADRD2 | |
| SCHEMBL7729810 | 0.91 | HTR2A (0.44) | SIGMAR1DRD4HTR2ADRD2 | |
| SCHEMBL7719772 | 0.81 | SIGMAR1 (0.47) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7719805 | 0.80 | SIGMAR1 (0.51) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7725090 | 0.80 | SIGMAR1 (0.51) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7725086 | 0.80 | SIGMAR1 (0.51) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7729583 | 0.80 | SIGMAR1 (0.55) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7729579 | 0.80 | SIGMAR1 (0.55) | SIGMAR1DRD4CXCR3LTA4HMC4R | |
| SCHEMBL7725264 | 0.76 | SIGMAR1 (0.53) | SIGMAR1DRD4CXCR3LTA4HMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468998-B1 | ANTAGONIZE SEROTONIN 2 RECEPTORS, SUPPRESS PLATELET AGGREGATION, IMPROVE PERIPHERAL CIRCULATION AND PROMOTE LACHRYMATION | MITSUBISHI PHARMA CORPORATION (JP) | 2002-10-22 | — | — | US | disclosed |