Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9885812 | 0.67 | — | — | |
| SCHEMBL3540174 | 0.61 | — | — | |
| SCHEMBL7453798 | 0.61 | — | — | |
| SCHEMBL29011264 | 0.61 | ALDH1A1 (0.41) | — | |
| SCHEMBL8918954 | 0.61 | KDM4E (0.30) | — | |
| SCHEMBL28195114 | 0.60 | — | — | |
| SCHEMBL2785733 | 0.60 | ALDH1A1 (0.30) | — | |
| SCHEMBL18611181 | 0.60 | — | — | |
| SCHEMBL28497472 | 0.58 | — | — | |
| SCHEMBL28047875 | 0.58 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355805-B1 | MULTIBINDING COMPOUNDS USEFUL IN TREATMENT AND PREVENTION OF METABOLIC DISORDERS SUCH AS OBESITY AND DIABETES | ADVANCED MEDICINE, INC. | 2002-03-12 | — | — | US | disclosed |
| EP-1085894-A1 | BETA 3-ADRENERGIC RECEPTOR AGONISTS | Advanced Medicine, Inc. (US) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999064053-A1 | β3-ADRENERGIC RECEPTOR AGONISTS | ADVANCED MEDICINE, INC. (US) | 1999-12-16 | — | — | WO | disclosed |