Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 1.00 |
| ▸ | HPGD | P15428 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982188 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL13599981 | 0.77 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL6277710 | 0.76 | KDM4E (0.81) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL2607467 | 0.76 | ALDH1A1 (0.72) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL7721153 | 0.75 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL8010723 | 0.74 | ESR2 (0.79) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL2854775 | 0.73 | HSD17B10 (0.57) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL13271457 | 0.73 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7180606 | 0.72 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A | |
| SCHEMBL13377500 | 0.72 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |