SCHEMBL772518

SCHEMBL772518

CCOC(=O)/C=C/c1ccc(N)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.73
CA7 P43166 3/20 0.73
CA9 Q16790 3/20 0.73
CA14 Q9ULX7 3/20 0.73
CA1 P00915 2/20 0.73
CA2 P00918 1/20 0.73
CYP3A4 P08684 2/20 0.63
TTR P02766 1/20 0.62
DPP4 P27487 1/20 0.62
MAOB P27338 1/20 0.60
FDPS P14324 1/20 0.54
LMNA P02545 1/20 0.51
CYP1A2 P05177 1/20 0.51
MAOA P21397 1/20 0.51
MET P08581 3/20 0.50
ESR1 P03372 1/20 0.49
POLB P06746 2/20 0.49
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
ALOX5 P09917 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27584641 1.00 CA12 (0.73) CA12CA7CA9CA14CA1
SCHEMBL772519 1.00 CA12 (0.73) CA12CA7CA9CA14CA1
Hydrochloric Acid SCHEMBL3936160 0.98 CA12 (0.71) CA12CA7CA9CA14CA1
Hydrochloric Acid SCHEMBL3936157 0.98 CA12 (0.71) CA12CA7CA9CA14CA1
SCHEMBL17457105 0.92 CA1 (0.63) CA12CA7CA9CA14CA1
SCHEMBL17457104 0.92 CA1 (0.63) CA12CA7CA9CA14CA1
SCHEMBL5059085 0.91 CA12 (0.86) CA12CA7CA9CA14CA1
SCHEMBL10939791 0.91 CA12 (0.86) CA12CA7CA9CA14CA1
SCHEMBL13957401 0.91 CA12 (0.86) CA12CA7CA9CA14CA1
SCHEMBL1260527 0.89 CA12 (0.83) CA12CA7CA9CA14CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754591-B HDAC, JAK and BET three-target inhibitor and preparation method and application thereof 山东大学 2024-01-05 CN claimed
CN-113754591-A HDAC, JAK and BET three-target inhibitor and preparation method and application thereof 山东大学 2021-12-07 CN claimed
US-10723998-B2 Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells NORTHEAST NORMAL UNIVERSITY (CN) 2020-07-28 US claimed
US-20180195039-A1 APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS NORTHEAST NORMAL UNIVERSITY (CN) 2018-07-12 US claimed
CN-101774918-A Preparation method of cinnamate derivates UNIV HUAQIAO 2010-07-14 CN claimed
CN-122095297-A Composition for forming cured film, alignment material, and phase difference material 2026-05-26 CN disclosed
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety CURIS INC (US) 2025-07-17 US disclosed
WO-2025088969-A1 COMPOSITION FOR FORMING CURED FILM, CURED FILM, ALIGNMENT MATERIAL, AND RETARDATION MATERIAL 日産化学株式会社 2025-05-01 WO disclosed
WO-2025023309-A1 COMPOSITION FOR FORMING CURED FILM, ALIGNMENT MATERIAL, AND PHASE-DIFFERENCE MATERIAL 日産化学株式会社 2025-01-30 WO disclosed
CN-113874470-B Composition for forming cured film, alignment member, and phase difference member 日产化学株式会社 2024-11-19 CN disclosed
CN-118239917-A HDACs inhibitor and preparation method and application thereof 山东大学 2024-06-25 CN disclosed
CN-113754591-B HDAC, JAK and BET three-target inhibitor and preparation method and application thereof 山东大学 2024-01-05 CN disclosed
US-4281019-A 4-[(Unsaturated or cyclopropylated alkyl)amino]phenyl compounds useful as hypolipidemic and antiatherosclerotic agents AMERICAN CYANAMID COMPANY (US) 1981-07-28 US disclosed
US-4259352-A 4-[Cycloalkyl- or cycloalkenyl-amino(cycloalkyl- or cycloalkenyl-alkenyl)amino]phenyl compounds, useful as hypolipidemic and antiatherosclerotic agents AMERICAN CYANAMID COMPANY (US) 1981-03-31 US disclosed
US-4211783-A Hypolipidemic and antiatherosclerotic novel 4-(aralkyl- and heteroarylalkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1980-07-08 US disclosed
US-4205085-A Hypolipidemic and antiatherosclerotic 4-(polyfluoroalkylamino)phenyl compounds AMERICAN CYANAMID COMPANY (US) 1980-05-27 US disclosed
EP-0003663-A2 Amino-substituted phenyl and heteroaryl compounds, process for their preparation and pharmaceutical compositions containing them AMERICAN CYANAMID COMPANY (US) 1979-08-22 EP disclosed
US-4136165-A SUNSCREEN AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-01-23 US disclosed
US-4101543-A DYES FOR CELLULOSE ACETATES, AROMATIC POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US disclosed
US-4094636-A DIAZOTIZATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195039-A1 APPLICATION OF ETHYL P-METHOXYCINNAMATE AND DERIVATIVES THEREOF IN MAINTAINING SELF-RENEWAL AND PLURIPOTENCY OF STEM CELLS XPA, MEP1A, EED CA12 4873/4885CA7 4841/4885CA9 4871/4885
US-10723998-B2 Application of ethyl p-methoxycinnamate and derivatives thereof in maintaining self-renewal and pluripotency of stem cells XPA, MEP1A, EED CA12 4873/4885CA7 4841/4885CA9 4871/4885
US-20250230169-A1 Phosphoinositide 3-Kinase Inhibitors with a Zinc Binding Moiety BAZ2A, BAZ2B, PI4KB CA12 3809/4885CA7 3949/4885CA9 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.