Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 20/20 | 0.64 |
| ▸ | RARB | P10826 | 20/20 | 0.64 |
| ▸ | RARG | P13631 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7621722 | 0.91 | RARA (0.53) | RARARARBRARG | |
| SCHEMBL7624482 | 0.90 | RARA (0.50) | RARARARBRARG | |
| SCHEMBL7623083 | 0.87 | RARA (0.63) | RARARARBRARG | |
| SCHEMBL7727128 | 0.86 | RARA (0.50) | RARARARBRARG | |
| SCHEMBL7619645 | 0.85 | RARA (0.63) | RARARARBRARG | |
| SCHEMBL1132581 | 0.84 | RARA (0.62) | RARARARBRARG | |
| SCHEMBL29367158 | 0.84 | RARA (0.62) | RARARARBRARG | |
| SCHEMBL7730938 | 0.83 | RARA (0.43) | RARARARBRARG | |
| SCHEMBL7624517 | 0.82 | RARA (0.48) | RARARARBRARG | |
| SCHEMBL7616809 | 0.82 | RARA (0.60) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358995-B1 | AGONIST FOR RETINOIC ACID RECEPTORS; CAN BE SUBSTITUTED FOR RETINOIC ACID AS PREVENTIVE AND THERAPEUTIC DRUGS FOR VARIOUS DISEASES OR CANCERS, SUCH AS ACUTE PROMYELOCYTIC LEUKEMIA. | EISAI CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| US-6258811-B1 | ADMINISTERING RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| US-6121309-A | SUCH AS 4-(2-(5-(7-FLUORO-4-TRIFLUOROMETHYLBENZOFURAN-2-YL)PYRROLYL)) BENZOIC ACID; RETINOIC ACID RECEPTOR AGONISM | EISAI CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| US-6110959-A | A RETINOIC ACID RECEPTOR AGONIST | EISAI CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0930075-A1 | METHODS FOR PREVENTING, INHIBITING OR TREATING GRAFT REJECTION REACTIONS IN GRAFT-VERSUS-HOST DISEASE (GVHD) AND ORGAN TRANSPLANTATION | Eisai Co., Ltd. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0889032-A1 | FUSED-RING CARBOXYLIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-01-07 | — | — | EP | disclosed |