Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50007 | 1.00 | TSHR (0.63) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL4461926 | 0.89 | TSHR (0.59) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1069813 | 0.88 | TSHR (0.77) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1471723 | 0.87 | TSHR (0.57) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL27877270 | 0.84 | TSHR (0.64) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL1908201 | 0.84 | TSHR (0.70) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| Phenol SCHEMBL10941463 | 0.83 | TSHR (0.46) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL26923317 | 0.83 | TSHR (0.59) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL311322 | 0.82 | TSHR (0.50) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 | |
| Alcohol SCHEMBL150777 | 0.81 | SMN1; SMN2 (0.58) | TSHRMAPK1ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403164-B1 | COATINGS HAVING A HETERO/POLYSILOXANE AND A METAL COMPOUND DERIVED FROM THE SUBSTRATE HAVING A MORE NEGATIVE FORMATION ENTHALPY, THEN CURING TO FORM AN INORGANIC NETWORK ENCLOSING AND/OR ANCHORING THE SPECIES | Institut für Neue Materialien gemeinnutzige GmbH (DE) | 2002-06-11 | — | — | US | disclosed |