Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.64 |
| ▸ | RAD52 | P43351 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10400554 | 0.83 | FAAH (0.60) | HRH3 | |
| SCHEMBL16795357 | 0.80 | HRH3 (0.74) | HRH3TSHRACHERAD52 | |
| SCHEMBL27760041 | 0.80 | HRH3 (0.76) | HRH3TSHRACHERAD52 | |
| SCHEMBL30777699 | 0.80 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL3571025 | 0.80 | HRH3 (0.79) | HRH3TSHRACHERAD52 | |
| SCHEMBL3580727 | 0.80 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL28036344 | 0.79 | HRH3 (0.59) | HRH3 | |
| SCHEMBL6471513 | 0.79 | HRH3 (0.75) | HRH3ACHERAD52 | |
| Jnj-5207852 SCHEMBL3577334 | 0.78 | HRH3 (1.00) | HRH3TSHRACHERAD52 | |
| SCHEMBL3572587 | 0.78 | HRH3 (1.00) | HRH3TSHRACHERAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399631-B1 | 3-AMIDO OR 3-SULFONAMIDO; EATING DISORDERS IN HUMANS, DOGS AND CATS | PFIZER INC. | 2002-06-04 | — | — | US | disclosed |