Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 8/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 8/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 8/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.41 |
| ▸ | CDK1 | P06493 | 5/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425514 | 0.82 | CDK2 (0.47) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL16884031 | 0.80 | CDK2 (0.41) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL23068035 | 0.79 | CDK1 (0.40) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL29788750 | 0.79 | CDK1 (0.40) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL17807786 | 0.79 | CDK1 (0.40) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL20251105 | 0.77 | CDK1 (0.39) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL7721294 | 0.76 | PDE10A (0.44) | CDK2CDK1CCNB1CCNE1TDP1 | |
| SCHEMBL30960739 | 0.76 | MEN1 (0.40) | CDK2CCNA2CCNA1CDK5CDK5R1 | |
| SCHEMBL30168571 | 0.76 | DYRK1A (0.50) | DYRK1ACDK1ADORA2AADORA1 | |
| SCHEMBL6770226 | 0.76 | DYRK1A (0.50) | DYRK1ACDK1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3402797-B1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-02-19 | — | — | EP | disclosed |
| US-10375962-B2 | Heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-13 | — | — | US | disclosed |
| US-20190021329-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| WO-2017121674-A1 | HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-07-20 | — | — | WO | disclosed |
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-6875765-B2 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10375962-B2 | Heterocycle derivatives as pesticides | DDT, ACHE, CBR1 | CDK2 463/4885CCNA2 697/4885CCNA1 137/4885 |
| US-20190021329-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, CBR1 | CDK2 463/4885CCNA2 697/4885CCNA1 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.