Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706817 | 1.00 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2RAB9AGAAGBA1 | |
| SCHEMBL5224625 | 0.97 | — | — | |
| SCHEMBL4818431 | 0.83 | — | — | |
| SCHEMBL776553 | 0.83 | GBA1 (0.44) | ALDH1A1SMN1; SMN2RAB9AGAAGBA1 | |
| SCHEMBL20571181 | 0.80 | — | — | |
| SCHEMBL23852886 | 0.75 | — | — | |
| SCHEMBL8699153 | 0.74 | SLC2A1 (0.41) | ALDH1A1SMN1; SMN2RAB9AGAAGBA1 | |
| SCHEMBL10996279 | 0.74 | GBA1 (0.39) | ALDH1A1SMN1; SMN2RAB9AGAAGBA1 | |
| SCHEMBL8698883 | 0.74 | GBA1 (0.39) | ALDH1A1SMN1; SMN2RAB9AGAAGBA1 | |
| SCHEMBL23054278 | 0.74 | GBA1 (0.39) | ALDH1A1SMN1; SMN2RAB9AGAAGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403610-B1 | ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-06-11 | — | — | US | disclosed |