SCHEMBL7727295

SCHEMBL7727295

N#CCc1c[nH]nc1-c1c(F)cccc1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.32
CACNG8 Q8WXS5 1/20 0.32
MAP4K1 Q92918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1224419 0.79 HSP90AA1 (0.38)
SCHEMBL31282219 0.76 ERBB2 (0.45)
SCHEMBL3845897 0.69 TTR (0.32)
SCHEMBL5223273 0.69 ACHE (0.37) MAP4K1
SCHEMBL29893592 0.66 HPGD (0.40)
SCHEMBL837981 0.66 HPGD (0.40)
SCHEMBL27502431 0.66 GRIA1 (0.39) GRIA1CACNG8
SCHEMBL29734785 0.66 TAAR1 (0.48)
SCHEMBL103401 0.66 TAAR1 (0.48)
SCHEMBL25411703 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6462049-B1 LOW TOXICITY AND PERSISTENT INSECTICIDES AND FUNGICIDES; PREVENTING ATTACHMENT OF AQUATIC ORGANISMS; ECOSYSTEM FRIENDLY; NONPOLLUTING NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2002-10-08 US disclosed