Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031966 | 1.00 | MAPT (0.40) | MAPTPPARGEPHX2ALDH1A1FAAH | |
| SCHEMBL11105339 | 0.95 | RARB (0.39) | MAPTPPARGALDH1A1RARBADRB3 | |
| SCHEMBL9146322 | 0.95 | RARB (0.39) | MAPTPPARGALDH1A1RARBADRB3 | |
| SCHEMBL11598712 | 0.87 | MAPT (0.44) | MAPTKMT2A | |
| SCHEMBL4577544 | 0.83 | ALDH1A1 (0.59) | MAPTALDH1A1RARBADRB3TSHR | |
| SCHEMBL9234376 | 0.83 | ALDH1A1 (0.59) | MAPTALDH1A1RARBADRB3TSHR | |
| SCHEMBL11531555 | 0.83 | KMT2A (0.55) | MAPTPPARGALDH1A1LMNAACACB | |
| SCHEMBL1966513 | 0.82 | CXCR1 (0.53) | FAAHCHRM1PDE4APTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL9192168 | 0.81 | ALDH1A1 (0.57) | MAPTALDH1A1RARBADRB3TSHR | |
| SCHEMBL19523213 | 0.81 | PLA2G10 (0.47) | MAPTEPHX2EPHX1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-61277657-A | — | — | None | — | — | JP | disclosed |
| WO-2021115560-A1 | NEW FYN AND VEGFR2 KINASE INHIBITORS | ROTTAPHARM BIOTECH S.R.L. (IT) | 2021-06-17 | — | — | WO | disclosed |
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| US-5942387-A | Combinatorial process for preparing substituted thiophene libraries | ELI LILLY AND COMPANY (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998057173-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PHENYLALANINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-17 | — | — | WO | disclosed |
| EP-0880558-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED INDANE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0285141-A1 | Mesomorphic compound and liquid crystal composition containing same | CANON KABUSHIKI KAISHA (JP) | 1988-10-05 | — | — | EP | disclosed |
| US-4775223-A | DISPLAY DEVICE | CANON KABUSHIKI KAISHA (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0267585-A2 | Fluoroalkane derivative, its composition and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1988-05-18 | — | — | EP | disclosed |
| EP-0258578-A2 | Liquid crystal compounds having ether tail moiety | POLAROID CORPORATION (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0255962-A2 | Optically active mesomorphic compound | CANON KABUSHIKI KAISHA (JP) | 1988-02-17 | — | — | EP | disclosed |
| EP-0237007-A2 | Fluoroalkane derivative and liquid crystal composition | CANON KABUSHIKI KAISHA (JP) | 1987-09-16 | — | — | EP | disclosed |
| JP-S61277657-A | (+)-4-(4'-(2-METHYLBUTYL)BENZOYL)RESORCYLIDENE-4-SUBSTITUTED ANILINE | SEIKO EPSON CORP | 1986-12-08 | — | — | JP | disclosed |
| EP-0175591-A2 | Lactic acid derivative, liquid crystal composition containing same and liquid crystal device | CANON KABUSHIKI KAISHA (JP) | 1986-03-26 | — | — | EP | disclosed |
| EP-0164814-A2 | Liquid crystalline ester compounds and mixtures thereof | Chisso Corporation (JP) | 1985-12-18 | — | — | EP | disclosed |
| US-4082428-A | AROMATIC ESTERS | SUNCRUX INCORPORATED (US) | 1978-04-04 | — | — | US | disclosed |